Urticaria - It's not only itch

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The maddening itch: an approach to chronic urticaria.

Chronic spontaneous urticaria (CSU) is defined as the presence of urticaria with daily or almost daily symptoms for 6 weeks or more. CSU affects 0.1%-0.8% of the population. Its pathogenesis involves autoimmunity, abnormalities in signal transduction, and the action of histamine on H1 receptors. Investigation of CSU should be guided by a thorough history and physical examination. A concise labo...

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Itch itch with not a wink of sleep

KEY CLINICAL MESSAGE A 55-year-old man of dark complexion presented with multiple extensive swellings over the chest, right upper arm, and left shoulder for 10 years. Swellings were hyperpigmented, firm, and intensely pruritic especially over the chest region. The swellings progressed in size, extended, and developed satellite lesions over its 10 years history.

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Itch and its inhibition by counter stimuli.

Recent studies have made significant progress in the knowledge of how itch sensation is processed, especially the molecular identity of neurons involved in itch signaling, both in the dorsal root ganglion and spinal cord. Despite these advances, the organization of these neurons in dorsal spinal cord circuits and how they interact with other somatosensory modalities, such as pain or temperature...

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Itch characteristics in five dermatoses: non-atopic eczema, atopic dermatitis, urticaria, psoriasis and scabies.

Itch is a frequent symptom in many diseases. Some studies have used questionnaires to evaluate pruritus by targeting a single type of dermatitis, for example, studying atopic dermatitis (AD) with the " Eppendorf Itch Questionnaire " (1, 2), and uraemic pruritus (3). Questionnaires have also been used to study psoriasis (4) and urticaria (5). The pathophysiological mechanisms of itch, especially...

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Maintenance of remission with low-dose olopatadine hydrochloride for itch in well-controlled chronic urticaria

BACKGROUND The long-term follow-up of chronic urticaria (CU) is important to ensure the adequate treatment of patients. Olopatadine hydrochloride is one of the second-generation nonsedating antihistamines. METHODS This study was designed to assess the optimal dose of olopatadine to suppress symptoms of chronic urticarial itch in well-controlled patients. After CU patients were treated with 10...

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ژورنال

عنوان ژورنال: Journal of Emergency Medicine, Trauma and Acute Care

سال: 2016

ISSN: 1999-7086,1999-7094

DOI: 10.5339/jemtac.2016.icepq.27